Inter-Individual Differences in Cognitive Tasks: Focusing on the Shaping of Decision-Making Strategies is a recent publication about the Mouse Gambling Task. It revealed about 30% of healthy mice displaying risk-averse choices while about 20-25% of mice make risk-prone choices. These strategies are accompanied by different brain network mobilization and individual levels of regional -prefrontal and striatal- monoamines.
The study also illustrates three ecological ways that influence drastically cognitive strategies in healthy adult mice:
• acute sleep deprivation, that behaviorally exacerbes already exciting extreme decision-making profiles,
• artificial sweetener exposure that increases the proportion of mice showing extreme decision-making profiles,
• exposure to a stimulating environment that decreases the proportion of mice showing extreme decision-making behavior.