Inter-Individual Differences in Cognitive Tasks: Focusing on the Shaping of Decision-Making Strategies is a recent publication about the Mouse Gambling Task. It revealed about 30% of healthy mice displaying risk-averse choices while about 20-25% of mice make risk-prone choices. These strategies are accompanied by different brain network mobilization and individual levels of regional -prefrontal and striatal- monoamines.
The study also illustrates three ecological ways that influence drastically cognitive strategies in healthy adult mice:
• acute sleep deprivation, that behaviorally exacerbes already exciting extreme decision-making profiles,
• artificial sweetener exposure that increases the proportion of mice showing extreme decision-making profiles,
• exposure to a stimulating environment that decreases the proportion of mice showing extreme decision-making behavior.
Chronic Sleep Debt (CSD), Acute Sleep Debt (ASD), sucrose or saccharin consumption and Enriched Environment (EE) conditions. Gradients of rigidity as well as risk taking or risk avoidance are represented by the arrows.
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