Category: Biology of Information
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exploring One Health
The eco-epidemiology of zoonoses is often oversimplified to host-pathogen interactions while findings derived from global datasets are rarely directly transferable to smaller-scale contexts. Through a systematic literature search, we compiled a dataset of naturally occurring zoonotic interactions in Austria, spanning 1975–2022. We introduce the concept of zoonotic web to describe the complex relationships between zoonotic…
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Shifting attention
The Internal Dominance over External Attention (IDEA) hypothesis (I referred to earlier) asserts, contrary to the traditional view of attention as being primarily externally oriented, that attention is inherently biased toward internal information. A related work on attention switching has been published: “Shifting attention between perception and working memory“ Most everyday tasks require shifting the…
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energetic cost of allostasis and allostatic load – do not stress
Chronic psychosocial stress increases disease risk and mortality, but the underlying mechanisms remain largely unclear. This article in Psychoneuroendocrinology outlines an energy-based model for the transduction of chronic stress into disease over time. The energetic model of allostatic load (EMAL) emphasizes the energetic cost of allostasis and allostatic load, where the “load” is the additional…
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Fast walkers have higher IQ and larger brains than slow walkers.
These findings are from a 5-decade cohort study of 904 participants in New Zealand published in @JAMANetworkOpen which tested the hypothesis that slow gait speed reflects accelerated biological aging at midlife. Slow gait was associated with multiple indices of compromised structural brain integrity, including smaller total brain volume, global cortical thinning, and reduced total surface…
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Andy Clark “How the brain shapes reality”
Philosopher and cognitive scientist Andy Clark challenges our conventional understanding of the mind’s interaction with the world. A great and entertaining lecture. I like the reflection with the reference to the weather forecast and how the forecast impacts “reality” perception. At the very least, understanding all those prediction-driven, precision-inflected, looping influences should bring us a…
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Why the simplest explanation isn’t always the best
Eva L. Dyer and Konrad Kording discuss in a commentary article “Why the simplest explanation isn’t always the best” an essential learning related to the article Phantom oscillations in principal component analysis (also available on BioRXiv) Dimensionality reduction simplifies high-dimensional data into a small number of representative patterns. One dimensionality reduction method, principal component analysis (PCA), often selects oscillatory…
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